AbstractNature defines the spatial boundaries between different phases using membranes, and the interfacial interactions are mediated by soft biopolymer interlayers that contain various carbohydrates. This Review provides a comprehensive overview on the interplay of generic and specific interactions at cell–cell and cell–tissue interfaces. A focus will be put on the combination of defined model systems, experimental techniques in real‐ and reciprocal space, and theoretical simulations.
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