A schematic diagram of the glymphatic flow pathway and its alteration by focused ultrasound that opens the blood‐brain barrier. In the lower part of the figure, gadolinium (small black particles) in the red arterial blood enters the brain and flows through into blue veins. Focused ultrasound (green waves in the upper part of the figure) allows particles to enter the interstitial space where they are carried by bulk flow into perivenular spaces and from which they are cleared by meningeal lymphatic vessels (green). Illustration by Hang Yu Lin. See Meng et al. on pp. 975–980, in this issue for details.
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