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Molecular genetics research in ADHD: Ethical considerations concerning patients' benefit and resource allocation

Lillian Geza Rothenberger · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · 2012

AbstractImmense resource allocations have led to great data output in genetic research. Concerning ADHD resources spent on genetic research are less than those spent on clinical research. But there are successful efforts made to increase support for molecular genetics research in ADHD. Concerning genetics no evidence based conclusive results have significant impact on prevention, diagnosis or treatment yet. With regard to ethical aspects like the patients' benefit and limited resources the question arises if it is indicated to think about a new balance of resource allocation between molecular genetics and non‐genetics research in ADHD. An ethical reflection was performed focusing on recent genetic studies and reviews based on a selective literature search. There are plausible reasons why genetic research results in ADHD are somehow disappointing for clinical practice so far. Researchers try to overcome these gaps systematically, without knowing what the potential future benefits for the patients might be. Non‐genetic diagnostic/therapeutic research may lead to clinically relevant findings within a shorter period of time. On the other hand, non‐genetic research in ADHD may be nurtur

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